General Questions


What is Flexineb® E3?

Flexineb® E3 is a simple to use, silent and portable equine nebuliser system without the standard noisy compressor, hoses, wires, and typical inconveniences of old horse nebulisers. The Flexineb® E3 is a revolutionary equine nebuliser that enables delivery of nebulised (inhaled) medications and natural therapies directly to the airways of the horse. It operates from a rechargeable battery powered controller and has a unique flexible mask interface with a clear aerosol chamber and medication cup.

Why use Flexineb® E3?

Respiratory problems in horses are frequently the cause of poor sportive performances and can also impact the daily wellbeing of an animal. Historically there were several known types of respiratory disease in horses such as RAO (recurrent Airway Obstruction), Heaves, COPD and Inflammatory Airway Disease(IAD) which are now known under the umbrella term ‘Equine Asthma’ which is graded into three categories, Mild, Moderate & Severe. Historically, the treatment options for respiratory disease, includes systemic administration of drugs using injections or the oral route, however administration via inhalation through horse nebuliser masks and inhalers are now considered to be a viable alternative way to treat respiratory disorders (including breathing, airway, or lung problems). Flexineb® is an easy-to-use delivery device that produces a very fine mist of aerosolized drug or natural therapy solution enabling you to deliver a variety of medications via inhalation for the horse. This has allowed thousands of horses globally, to continue their working careers, rehabilitate from acute illness and allows owners to manage their horses’ respiratory issues efficiently in the long term.

Where can I find information on the benefits of Nebulisation in horses and Aerosol Therapy?

Aerosol therapy offers the benefit of delivering nebulised medication directly to the site of infection in the airways of the horse rather than going indirectly to the problem by delivering the drug orally or by injection. Please check out our Information page for further information on the benefits of Aerosol Therapy.

Will Flexineb® help chronic airway inflammation and/or Equine Asthma?

Flexineb® has the ability to deliver a wide range of medications commonly used to treat airway inflammation & equine asthma. Your veterinarian will prescribe medications suitable for your horse’s condition and combined with further management of your horse’s environment (bedding/forage stabling away from common irritants etc.) many veterinarians & horse owners have reported significant improvements in their horse’s wellbeing, check out the Testimonials section of our website.

Is Flexineb easy to use and does it come with Instructions?

Yes, Flexineb is very easy to set-up and each system comes with a User Manual. You can also download our Flexineb+ App to your phone for more information on Getting Started and information on Flexineb.

Will Flexineb help my horse?

Respiratory disease and allergies vary in severity across the equine species – no two horses are the same and neither are their respiratory problems. Helping your horse by incorporating Flexineb® into their routine will certainly help them maintain healthy airways. However, you will also need to manage their environment carefully to maximise fresh air circulation and minimise airborne dust and allergens in their breathing zone. Your horse may also be prescribed medications by your veterinarian depending on the severity of the issue, and your horse may need long term management.

What is different about the Flexineb® E3 compared to other equine nebulisers on the market?

Our Flexineb vibrating mesh nebuliser was designed specifically for the comfort of the horse and ease of use for the caregiver. The robust, portable, silent, lightweight design lends itself to better compliance in looking after your horse and gives the owner freedom to nebulise their horse on the go.

Once your horse is familiar and relaxed wearing Flexineb® and it is safe to do so you can walk with the horse during nebulisation to encourage deeper breathing and deep inhalation of nebulised solutions. The Flexineb® is also unique in that it can efficiently nebulise a broad range of medications and natural solutions for maintaining and treating your horses’ airways.

We are here to help you when things go wrong and offer advice in getting the best from your Flexineb® device. Flexineb® is a fully serviceable product.

Older traditional horse nebulisers are based on noisy air compressors or high frequency ultrasonic sound waves to generate the aerosol mist. Both these technologies need to be plugged into mains electricity and have hoses connected to the mask. You cannot walk your horse with these type devices. They are cumbersome to use and limited in the range of solutions they can nebulise, and delivery time is typically slow.

Compressor based systems force compressed air into the mask leading to major aerosol leaks and losses from an open mask design.

Ultrasonic based technologies produce high volumes of aerosol but there can be major losses in the long hose system connected to the mask. Medication integrity may be adversely affected by heating due to the high frequency crystal method of generating the mist.

Can I use Flexineb Everyday or multiple times per day?

Yes, you can use your Flexineb® several times per day if required or prescribed.

It is very important to follow the cleaning instructions in the User Manual and Video Instructions to maintain the system and avoid cross contamination if used on multiple horses.

My vet has no experience of the technology, where can I get advice on drug dosage?

We can consult with and supply this information directly to your veterinarian if they contact us directly on

What medications can I use with Flexineb®?

Flexineb® can deliver a broad range of medications commonly used to treat equine asthma and respiratory infections.

We can provide this information directly to your veterinarian on request to

Some examples of drug categories that have been successfully nebulised using the Flexineb® E3 are: — Antibiotics — Corticosteroids — Bronchodilators — Mucolytics.

Please note the viscosity of the drug will affect the nebulisation rate and delivery time. To overcome this some drugs can be diluted with saline solution to increase the nebulisation rate and delivery time.

Please note the following are NOT to be nebulised with Flexineb® and may damage the medication cup: AZIUM, VET ONE DEX, VEDCO DEX, DUPHACORT, RESPRADIL, VETADINE, BROMINE, MILTON / BLEACH, COLLOIDAL SILVER, DE-IONISED WATER, IONISED WATER.

My veterinarian has prescribed a human puffer (MDI) for my horse to inhale, can I use a Metered Dose Inhaler with the Flexineb® E3?

Yes, each Flexineb® system is sold with an MDI adapter, allowing you to deliver MDIs to your horse using the Flexineb® Mask System. Flexineb® really allows you huge flexibility and options on medication choices for your horse. Check our User Manual for MDI set-up.

Can I mix liquid medications in the cup to save time?

This is not advisable for therapeutic reasons and medication cup life reasons.

Mixing medications in the Flexineb® medication cup may impact on your horse’s clinical response and may also reduce the operation life of medication cup.

Do you supply medications?

We do not supply medications for use with Flexineb® – your veterinarian will prescribe and dispense medications or provide you with a prescription to purchase from your pharmacy.

What arrives when I receive a Flexineb® E3 and can I start using it immediately?

Flexineb® E3 Complete Nebuliser System has everything you need to begin nebulising your horse. Normal 0.9% saline solution is included for you to begin you nebulisation journey and familiarize yourself and your horse with their new nebulizer.

Do you have testimonials from veterinarians & customers who already use Flexineb®

Yes, check out our Testimonial page to read our customers experience of using Flexineb®. Our social media channels frequently post customer experiences also.

Do you have Clinical Research on equine nebulisation and Flexineb®?

Yes, refer to our Clinical Publications page for some reading.

How do I clean my Flexineb® unit?

Check out our User Manual and Video Instructions for cleaning instructions.

Please note the Flexineb® Controller must be used and stored in dry conditions.

Don’t forget to remove it when washing the Mask!.

Can my horse still breathe with the mask on?

Yes, the Flexineb® mask has a valved system to allow fresh air in at the top of the chamber during inhalation and exhaled air out through the bottom when the horse exhales.

When introducing your horse to Flexineb® for the first time you can leave out the medication cup and open the exit valve vents at the bottom of the mask by rotating it.

Once your horse is relaxed and familiar with wearing Flexineb® you can plug in the medication cup and close the exit valve slowly to activate the valve system. Once they are relaxed and breathing normally you can begin nebulisation of normal saline solution.

You should see the chamber filling and emptying of aerosol mist each time your horse inhales. If this is not happening the mask may be too loose on the muzzle of the horse or the exit valve is not fully closed. You can also walk the horse to encourage deeper breathing as they can shallow breath if standing.

Ensure the mask creates a good seal around the muzzle of the horse.

Always check the Inlet and Exit Valves are working ok and not blocked or taped up before use.

What is the warranty on Flexineb®?

Information on Warranty can be found in your User Manual.

Are Spare Parts readily available for Flexineb®?

Yes, Flexineb® is a fully serviceable product, and our distributors carry spare parts for servicing.

Find your local distributor here.

Are there discounts or sales coming up?

Some of our global distributors run promotional offers throughout the year – you will need to keep an eye on their social media channels to see these.

Do you offer payment plans?

Some of our distributors offer payment plans. Check our Distributor Page to find your local agent and contact them directly to see if they offer payment plans.

I can’t find the answer to my question?

Please check out the other sections in our FAQs or contact your local distributor. Alternatively email us at with any technical questions and we will help you.