The Flexineb E3 is an equine nebulizer. The Flexineb E3 converts liquid solutions which are intended to act in the lungs into a fine mist to be inhaled by the horse.

The Flexineb E3 is silent in use, portable, flexible and comfortable, safe, and easy to use. The Flexineb E3 is available in 3 sizes to suit your horse’s needs, with multiple colours available.

The horses lungs make a fundamental contribution to the wellbeing and performance of our horses. Unfortunately, they are under constant attack from external influences..

• Environmental factors such as dust, pollen, mould, pollution and weather conditions
• Stressful situations like stabling, travelling, and competition
• Bacteria and viruses in the air
• And many more

Respiratory tract illnesses are the second leading cause of health problems in horses, surpassed only by musculoskeletal conditions. Unlike external injuries to your horse, irritations of their lungs are invisible. We often only react when the first symptoms, such as coughing, appear. Preventative measures need to be taken to avoid the development of irreversible damage to the lungs and to safeguard their health and quality of life.

Inhalation is an easy and non-invasive way to provide your horse with the targeted support they need, whether preventative, supportive or therapeutic. Make Flexineb E3 part of your horse’s daily routine.

The Flexineb E3 Complete Set has everything you need to begin nebulizing your horse. Saline solution 0.9% is included for you to begin you nebulization journey and familiarize yourself and your horse with their new nebulizer.

• Flexineb E3 Mask Set
• Flexineb E3 Controller including Battery
• Flexineb E3 Connector Cable
• 2 x 10ml Flexineb E3 Cups (grey)
• Flexineb Cup Volume Extender
• Flexineb E3 Charger
• Metered Dose Inhaler Attachment
• 500ml 0.9% saline solution
• 500ml distilled water for cleaning
• Flexineb Storage Case

The frequency of use largely depends on the specific substances being nebulized and the recommendations of your veterinarian. As a general guideline, you can use the Flexineb E3 as often as needed, but it’s always best to consult with your veterinarian to ensure the most appropriate care for your horse’s respiratory health. Regular veterinary advice is essential when managing respiratory conditions.

What Works Well—and What Doesn’t:

✅ Works well: Water-based solutions that are thin and fully dissolved (like salt in water).

⚠️ May work: Slightly thicker liquids or mild suspensions (like sugar water with a bit of residue). Some compounded substances aren’t suitable for nebulization and may cause the cup to wear out faster.

❌ Not suitable:

• Thick or sticky substances (like syrup or honey)
• Oils (e.g., essential oils)
• Suspensions with visible particles (like sand in water)

If you're using a water-based liquid that's too thick, dilution may help. But if the liquid is oil-based, diluting won't make it suitable for use.

If you're a horse owner looking for information on appropriate substances for nebulization, we recommend consulting with your veterinarian, who can provide tailored advice based on your horse's specific respiratory condition and medical history.

Please note the following is a non-exhaustive list of substances that are not suitable for nebulizing using Flexineb: RESPRADIL, VETADINE, BROMINE, MILTON / BLEACH, COLLOIDAL SILVER, DE-IONISED WATER, IONISED WATER, SALINE & CHELATED SILVER (MIXED), IODINE.

Yes, you can use Metered Dose Inhalers (MDIs) with the Flexineb E3, as it comes with an MDI attachment for this purpose. Instructions on how to use the Flexineb E3 for MDI use are included in the user manual.

The Flexineb warranty covers various components for different periods as follows:

• Controller Warranty: 2 years from the date of purchase, covering free replacement or repair if the issue is confirmed not to be due to user error. Exclusions: Water damage, incorrect charger usage, and physical damage due to impact are not covered.
• Battery Warranty: 6 months from the purchase date.
• Other Parts Warranty: 2 years for all parts.
• Flexineb E3 Cup: The Flexineb E3 cup is considered a wearable part and is not covered under the standard warranty. Its lifespan is affected by the substances nebulized and how well it is maintained.

Flexineb E3 Cup Lifespan

The E3 cup is designed for an expected lifespan of up to 100 uses when used exclusively with 10ml of 0.9% saline solution. If other solutions are used, the lifespan may be reduced by up to 50%. Users who nebulize specialized or medicated substances should expect a shorter duration of effective use.

Proof of purchase is required for all warranty claims, and claims must be made directly to the seller with the necessary documentation. Proper maintenance and following usage guidelines will help maintain the longevity of the Flexineb and ensure warranty coverage.

Warranty on Replacements: The warranty does not reset after a replacement. For example, if the controller is replaced after 1 year, the remaining 1 year of warranty still applies.

For any questions or concerns, don’t hesitate to reach out to your seller for assistance.

Yes, spare parts for Flexineb are available for purchase directly from Nortev or through many of our Flexineb wholesalers.

If you can’t find the answer to your question, please contact us.

A metered dose inhaler (MDI) and a nebulizer, like the Flexineb, are both devices used to deliver substances to the lungs. The main differences between the two lie in their delivery method, the areas of the airways they reach, and their ease of use:

Metered Dose Inhaler (MDI):

• An MDI is a handheld device that releases a specific dose in the form of a fine aerosol spray.
• It typically requires coordination between the handler and the animal to ensure proper inhalation.
• While MDIs can deliver substances to the upper airways, reaching the lower airways requires precise technique and is often more challenging.
• Using an MDI effectively can be more difficult, especially with larger animals or those not accustomed to the device.

Nebulizer (e.g., Flexineb):

• A nebulizer is a device that converts liquids into a fine mist or aerosol that can be inhaled into the lungs.
• The nebulizer delivers a continuous aerosol mist while in operation.
• Nebulizers can effectively deliver substances to both the upper and lower airways, making them suitable for a wider range of respiratory conditions.
• Devices like Flexineb are often preferred for animals that may struggle with inhaler coordination or require the mist to reach deeper into the lower airways.
• Nebulizers are typically easier to use, as they require less technique and can stay in place while the animal inhales the aerosol, offering a more hands-free approach.

In summary, while both MDIs and nebulizers can be effective, nebulizers offer distinct advantages such as delivering substances to both the upper and lower airways and being easier to use for handlers. This makes devices like Flexineb a preferred choice, especially in veterinary settings with horses and other large animals.

Flexineb is designed for long-term use, thanks to its durable construction and dependable performance. However, whether it’s appropriate for ongoing use in a specific case depends on factors like the horse's particular respiratory condition, the care plan in place, and any individual health considerations. It's important to consult with your veterinarian for personalized advice on long-term respiratory care. Your veterinarian can guide you on how frequently and for how long to use Flexineb, based on the animal’s needs and how they respond to the process.

Flexineb was created by Nortev Ltd.

Nortev Ltd., founded in 2008 by two engineers, Declan Moran and Gavan O’ Sullivan, is based in Galway, Ireland. Nortev is dedicated to developing innovative inhalation devices for animals with the unique design and technology.

Nortev has since grown to become a leader in the design, manufacture, and commercialization of portable nebulizers for horses and companion animals, distributing its products worldwide in Europe, North America, Australasia, and the Middle East. Customers include well-known veterinary clinics, stud farms and horse trainers as well as professional and leisure riders.

Nortev is committed to serving natural needs of horses and small animals through constant improvement of our Flexineb devices. The respiratory system of each animal is fundamental for their quality of life, which is why we developed the Flexineb with your animal in mind.

The Flexineb E3 Cup is the only consumable part in the Flexineb system and will need periodic replacement due to wear. Over time and with use, the gold mesh inside the cup can degrade. The E3 cup is designed for an expected lifespan of up to 100 uses when used exclusively with 10ml of 0.9% saline solution. If other solutions are used, the lifespan may be reduced by up to 50%. Users who nebulize specialized or medicated substances should expect a shorter duration of effective use. It's advisable to keep a backup cup in stock. Proper cleaning of the cup after every use can help maximize its lifespan, as well as using separate cups for different substances. Other parts of the Flexineb E3 are not considered wearable and generally do not require periodic replacement unless damaged.

After each use, thoroughly clean and dry all components of your Flexineb according to the instructions to prevent residue buildup and ensure optimal performance. Store your Flexineb in a clean, dry location away from direct sunlight and moisture. Avoid extreme temperatures or humidity, as they can affect its functionality.

Cleaning your Flexineb unit involves two separate procedures: one for the Flexineb E3 Cup and another for the other parts of the set.

For the Flexineb E3 Cup:

Clean the Flexineb E3 Cup after each use

• Always protect the electronics using the clear cap
• Clean with distilled water and one drop of mild dish soap
• Rinse thoroughly and air dry
• Never use sharp objects
• Do not use harsh or chemical cleaners

Video instructions: Scroll to instructions

For other parts of the Flexineb E3:

• Remove electronic components (controller, cable, Flexineb E3 Cup) before cleaning
• Completely disassemble the set for cleaning
• Use a disinfectant spray and water to gently wash the parts, avoiding harsh chemicals
• Rinse the inside of the mask and chamber thoroughly and dry the parts with a clean tissue paper
• Store the cleaned parts in a cool, dry place, ensuring the electronics remain dry and safe

Video instructions: Scroll to instructions

By following these cleaning instructions and utilizing the provided resources, you can maintain the cleanliness and functionality of your Flexineb unit for optimal performance.

For the Flexineb E3 Cup:

• Clean with distilled water and one drop of mild dish soap
• Do not use harsh or chemical cleaners

Video instructions: Scroll to instructions

For other parts of the Flexineb E3:

• Use a disinfectant spray and water to gently wash the parts, avoiding harsh chemicals
• Ensure the electronics remain dry and safe

Video instructions: Scroll to instructions

We recommend cleaning the Flexineb system after every use to maximize its lifespan and prevent cross-contamination.

If you are located in

• Belgium
• Bulgaria
• Croatia
• Cyprus
• Czech Republic
• Denmark
• Finland
• France
• Greece
• Hungary
• Ireland
• Italy
• Luxembourg
• Malta
• Poland
• Portugal
• Slovakia
• Slovenia
• Spain
• Sweden

you can purchase your Flexineb directly from us.

If you are located elsewhere, you can find your local distributor here: Local Retailers

The Flexineb E3 Cup is the heart of the Flexineb system. It’s the part that holds the liquid and transforms it into the fine mist. This happens through a delicate, 18-carat gold-plated  mesh that vibrates 90,000 times per second, creating the aerosol that your horse inhales.

The Flexineb E3 Cup works hard and contains sensitive components, therefore, it is a consumable part that naturally wears out over time and should be replaced periodically to maintain consistent performance.

Choosing the right Flexineb E3 Cup colour depends on the type of liquid you’re nebulizing:

• Grey Cup – Ideal for most thin, water-like solutions. If your liquid flows easily, like salt fully dissolved in water, the grey cup is usually the best fit.
• Green Cup – Designed for slightly thicker liquids or mild suspensions. Think of a liquid with sugar partially dissolved, or something just a little thicker than water. If your solution struggles to nebulize in the grey cup—even on higher power settings—the green cup is a better choice.
• Blue Cup – Best used for small volumes of thin liquids.

Getting the Best Results:

• Start with the grey cup on power level 1.
• Increase the power only if needed—slower nebulization is often more effective.
• Avoid using the green cup with very thin solutions, as it may nebulize too quickly and cause dripping.
• Use a separate Flexineb E3 Cup for each type of substance to help extend cup life and maintain performance.

What Works Well—and What Doesn’t:

• ✅ Works well: Water-based solutions that are thin and fully dissolved (like salt in water).
• ⚠️ May work: Slightly thicker liquids or mild suspensions (like sugar water with a bit of residue). Some compounded substances aren’t suitable for nebulization and may cause the cup to wear out faster.

❌ Not suitable:

• Thick or sticky substances (like syrup or honey)
• Oils (e.g., essential oils)
• Suspensions with visible particles (like sand in water)

If you're using a water-based liquid that's too thick, dilution may help. But if the liquid is oil-based, diluting won't make it suitable for use.

Because the Flexineb E3 Cup includes delicate components like a vibrating mesh, it’s a consumable part and will need replacing over time to maintain proper function.

The lifespan of the Flexineb E3 Cup varies depending on the substances nebulized within it and the cleaning frequency. The cup is lined with gold-plated mesh, which can corrode over time due to certain substances. Thicker substances may also gradually clog the mesh. Using separate cups for different substances is recommended to maximize lifespan and avoid cross-contamination.

Additionally, using too high of a power level for the substances being nebulized can damage the cup. The E3 cup is designed for an expected lifespan of up to 100 uses when used exclusively with 10ml of 0.9% saline solution. If other solutions are used, the lifespan may be reduced by up to 50%. Users who nebulize specialized or medicated substances should expect a shorter duration of effective use. It's advisable to keep a backup cup in stock.

For the grey-coded Flexineb E3 Cup, the nebulization process typically takes approximately 8-12 minutes to nebulize 10ml of 0.9% saline solution. Minor variations in the nebulization time for the same substance at the same volume should not be a cause for concern.

The flow rate is dependent on the substance being nebulized and the power level used. Thicker substances will require more time to nebulize. If a substance appears to be nebulizing at a slower-than-expected rate, you may consider increasing the power level. For thicker substances that still struggle at power level 3 with the grey-coded cup, switching to the green-coded cup may be necessary.

You'll know it's time to change your Flexineb E3 Cup if, despite appropriate usage and cleaning, it suddenly stops working or performs abnormally. Signs may include substances dripping from the cup instead of aerosolizing, or decrease in performance. Visually inspect the cup for signs of wear. If you notice these signs, it's time to replace the cup. Periodically replacing the Flexineb E3 Cup is essential, so having a backup is advisable. 

The three numbers on the left side of the controller indicate the power level. When you press the button to turn on the controller, it automatically starts at power level one. Pressing it a second time will set it to power level two, and pressing it a third time will set it to power level three

We recommend using the lowest power setting necessary to effectively nebulize your substance. Using a higher power level than needed can cause the substance to pass through the cup too quickly, resulting in less efficient nebulization. If you notice that the substance is dripping from the Flexineb E3 Cup, it may be that the power level you are using is too high.

For thinner substances like 0.9% saline, power level 1 is suitable when using a grey-coded cup. Higher power levels are needed only for thicker substances. Start with power level one, and only increase the power level if needed, such as if the substance struggles to nebulize.

Operating time from a new fully charged battery is approximately 6 hours.

When you press the button to turn on the controller, it automatically starts at power level one. Pressing it a second time will set it to power level two, and pressing it a third time will set it to power level three.

The three lights on the right represent the charge status of the controller. During use you will see the Battery GREEN LED drop down through the levels. When the battery is low the bottom LED will eventually change from GREEN to RED to indicate charging is required. If the low battery RED LED is ignored then the bottom LED will eventually flash RED and power off the controller until charging is completed.

While charging, the Battery LEDs will roll to indicate charging. The top LED will stay on constantly to indicate that charging is completed.

Please only use the original Flexineb charger as use of an alternative charger will void warranty and damage the internal circuit board, which may present a risk of fire or explosion.

While charging, the Battery LEDs will roll to indicate charging. The top LED will stay on constantly to indicate that charging is completed.

Please only use the original Flexineb charger as use of an alternative charger will void warranty and damage the internal circuit board, which may present a risk of fire or explosion.

If a battery is fully discharged it can take four to five hours to fully recharge. 

Please only use the original Flexineb charger as use of an alternative charger will void warranty and damage the internal circuit board, which may present a risk of fire or explosion.

When the battery is low the bottom right LED will eventually change from GREEN to RED to indicate charging is required. If the low battery RED LED is ignored then the bottom LED will eventually flash RED and power off the controller until charging is completed.

Please only use the original Flexineb charger as use of an alternative charger will void warranty and damage the internal circuit board, which may present a risk of fire or explosion.

We offer three sizes of masks along with a Mask Seal Optimizer to ensure a proper fit for your horse.

Available sizes:

• Standard (to fit muzzle 45-55cm)
• Small (to fit muzzle 35-45cm)
• Large (to fit muzzle 55-65cm)

Choosing the right size mask is crucial to ensure a tight seal and maximize the effectiveness of the nebulization process.

Please refer to our size guide for detailed information on selecting the correct size for your horse. This guide provides valuable assistance in determining the most suitable mask size based on your horse's dimensions and facial structure.

Yes, the mask is available in a range of colours including blue, black, pink, green, and red. However, please note that not all colours may be available in every size option. We recommend checking the available colour options for the specific size you require when making your selection.

To ensure that the mask is fitting correctly, follow these steps:

Check that the mask comfortably covers the horse's nose with minimal gaps between the muzzle and the mask. A tight seal should form for optimal performance.

When the Flexineb E3 is turned on, observe the aerosol holding chamber filling and emptying with each inhalation of the horse. If the chamber does not empty, the first possible cause is an improper fit of the mask. Consider using our Mask Seal Optimizer to improve the fit and seal.

If the issue persists, it may indicate that the horse is not breathing deeply enough. A gentle walk can be carried out while using the Flexineb E3 to encourage deeper breathing.

For further guidance on achieving the correct fit and troubleshooting, please refer to our size guide.

The mask is made from a special thermoplastic elastomer material. This material is non-porous, pliable, and durable, allowing for a comfortable fit, easy cleaning, and prolonged use. The mask does not contain any latex.